THE RESEARCH ON THE ISOLATION OF ANTHRAGLYCOSIDE OF LEAVES OF CASSIA ANGUSTIFOLIA VALH (FABACEAE)

Abstract

Cassia angustifolia is not widely cultivated in Vietnam, but is a valuable medicinal plant that has been studied by scientists around the world for a long time. For our country, it seems that this plant is still very new, but now it was brought to plant in Tuy Hoa, Phu Yen and initial research in the country about this plant. The effect of this tree is used to treat stools, constipation, indigestion, lobed lateral abdominal ... Many studies have demonstrated the laxative of anthraglycoside compounds derived from this plant as aglycol anthranoids (rhein, aloe emodin, chrysophanol) and anthraglycosides (rhein monoglycoside, aloe emodin mono glycoside, sennosid A, B, C, D, G, aloe-emodin dianthron glycoside). [1]

In this scientic article, the pure anthraglycoside compound Aloe emodin was isolated from 2.5 grams of total leaves of Cassia angustifolia Vahl. Their chemical structures are elucidated by analytical methods (IR, UV, MS, 1H-NMR) to determine the aloe-emodin. This is the first study on the isolation of Aloe emodin from Cassia angustifolia Valh of Vietnam in recent years.