A COMPREHENSIVE REVIEW OF DISEASE KNOWLEDGE, PERCEIVED SUSCEPTIBILITY AND COMPLIANCE BEHAVIORS AMONG POST-KIDNEY TRANSPLANT PATIENTS: INSIGHTS FROM GLOBAL AND VIETNAMESE STUDIES

Abstract

Chronic kidney disease (CKD) represents a significant global public

health challenge, with kidney transplantation serving as the most effec-

tive treatment for end-stage renal disease (ESRD). However, the success

of kidney transplantation is contingent not only upon the surgical pro-

cedure but also on patient adherence to post-transplant care, including

medication regimens, lifestyle modifications, and regular follow-up. This

literature review aims to systematically synthesize global and Vietnamese

studies on the impact of disease knowledge, perceived susceptibility, and

compliance behaviors among post-kidney transplant patients. Key find-

ings reveal that higher levels of disease knowledge and perceived sus-

ceptibility are strongly associated with better adherence and improved

patient outcomes. However, cultural beliefs and socio-economic barriers

significantly affect compliance behaviors, especially in low- and middle-

income countries like Vietnam. The review highlights the importance of

culturally tailored interventions to enhance patient education and sup-

port, which are critical for improving long-term transplant outcomes.

Recommendations for future research include the need for longitudinal

studies and the development of targeted interventions to address these

specific barriers in different cultural contexts.